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2025 (English)In: Abstract book: I.S.P.O. 20th World Congress, Stockholm, Sweden, 16-19 June 2025, 2025, p. 130-131Conference paper, Oral presentation with published abstract (Refereed)
Abstract [en]
BACKGROUND
Lower limb amputation (LLA) compromises key functional areas such as gait, balance, functional mobility, increased falls risk and fear of falling (1,2). Training interventions have been developed to improve mobility and balance confidence, broadly classified into prosthetic (e.g. microprocessor knees, energy storing feet) and therapeutic (e.g. exercise, virtual reality). Despite the range of treatment, previous reviews (3,4) have not clearly differentiated the effects of specific treatment types, limiting clinicians' ability to make informed decisions to improve these key functional outcomes.
AIM
To determine the effectiveness of different treatments designed to improve gait, balance, functional mobility, falls incidence, and fear of falling in people with LLA.
METHOD
A systematic review was conducted across 6 databases. Inclusion criteria encompassed therapuetic treatment of the identified outcomes. A multi-level meta-analysis accounted for correlations between multiple effect sizes from the same study, allowing for a more comprehensive evaluation both within and between studies. This approach is appropriate when studies report multiple outcome measures assessing the same underlying construct (e.g., gait), leading to correlated effect sizes within studies. Subgroup analysis determined differences in treatment type effectiveness. Effect sizes were calculated as standardized mean differences (SMDs) using Hedges' g, which corrects for small sample bias. SMDs can be interpreted using Cohen's benchmarks (small = 0.2, moderate = 0.5, and large = 0.8 effects).
RESULTS
Of 4,220 articles, 16 were analyzed. Treatments included proprioceptive neuromuscular facilitation (PNF, n = 2), exercise (n = 8), computerized balance training (CBT, n = 1), cognitive training (n = 3), and virtual reality (n = 4). Most studies were randomized controlled trials (n = 15), with sample sizes from 5 to 154 participants (73% male overall). Collectively, treatments moderately improved gait (SMD = 0.54) and balance (SMD = 0.47), and had small to moderate improvements in functional mobility (SMD = 0.30) and fear of falling (SMD = 0.27). Table 1 characterizes treatment effects.
DISCUSSION AND CONCLUSION
Cognitive training and virtual reality statistically significantly improved gait and balance respectively. Despite these promising results, further research is needed to align statistical improvements with meaningful patient benefits. Understanding the factors that modulate intervention effectiveness will be crucial for developing optimized rehabilitation protocols tailored to individual needs.
REFERENCES
1. Miller WC. Phys Ther. 2002.
2. Miller WC. Disabil Rehabil. 2004.
3. Edward M. POI. 2024.
4. Abou L. Clin Rehabil. 2022.
National Category
Physiotherapy
Identifiers
urn:nbn:se:hj:diva-69325 (URN)
Conference
I.S.P.O. 20th World Congress, Stockholm, Sweden, 16-19 June 2025
2025-07-142025-07-142025-10-13Bibliographically approved