The chapter focus on copyright as a possible an additional form of intellectual property protection for engineered DNA sequences. Considering the evolving conception of copyright subject matter, the current narrowed patent-eligible protection over living organisms and the advance of emerging technosciences like synthetic biology, the chapter looks with a renewed interest to copyright law as an additional potential form of protection for engineered biological creations. In particular, the contribution of this chapter is to reveal that copyright seems not only flexible enough to handle contemporary technologies producing living organisms, but also socially preferable to patent protection for accessing and using essential public knowledge assets in the life sciences.