Transdisciplinary research (TDR) has been the subject of discourse in the past few decades, but has not been studied much in the context of engineering problems. Many engineering problems can be characterized as ill-defined, like open innovation, adoption of new technology, business development, and the adoption of the Industry 4.0 concept. Transdisciplinary engineering research (TDER) is also performed in large projects by multi-disciplinary teams, as in TDR projects, including stakeholders and people from practice. Such projects may last long, often years. In such large projects, the involved disciplines should include both engineering disciplines as well as disciplines from social sciences. In this paper we address the challenges that exist in adopting a TDER approach. Universities need to prepare students to work in TDER projects. We discuss the current situation in transdisciplinary engineering education (TDEE) and identify challenges that need to be addressed for including TDEE in curricula. The paper ends with a summary and ideas for further research.