Today's digital products, services and experiences need to be designed with accessibility in mind in order to provide equal opportunities in use and enjoyment for the growing group of users with permanent, temporary and situational impairments. However, the topic still seems to be an afterthought in practice. With the research question 'What are the enablers and inhibitors for integrating accessibility into digital design processes from a systemic perspective?', this thesis aims to identify factors that drive or hinder accessibility efforts among design practitioners in Germany and how these factors may interrelate. Accessibility integration is therefore defined as a system. The research is based on a qualitative study using semi-structured interviews with four UX Designers, two UI Designers and one Chief Creative Officer with varying experiences regarding accessibility in past projects. By conducting a content analysis, the responses are grouped into categories and further visualized in the form of system archetypes to understand systemic behavior. The findings indicate that integration of accessibility into digital design processes is influenced by many enabling and inhibiting factors, of technical, individual, societal, institutional, regulatory, economic and financial as well as cliental and organizational nature, turning the topic into a complex, wicked problem. While economic reasons were a dominant force driving the system's behavior, it appears that the underlying mental models of all actors involved are significantly contributing to the state of accessibility in design practice.