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Xylitolens påverkan på Streptococcus mutans: En allmän litteraturstudie
Jönköping University, School of Health and Welfare.
Jönköping University, School of Health and Welfare.
2024 (Swedish)Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesisAlternative title
Influence of xylitol on Streptococcus mutans : A general literature study (English)
Abstract [sv]

Xylitol har påvisats förebygga karies som orsakas av Streptococcus mutans, en viktig kariespatogen. Syfte: Syftet med denna litteraturstudie var att beskriva xylitolens påverkan på Streptococcus mutans. Metod: Studiedesignen utgjordes av en allmän litteraturstudie som sammanställer resultatet av tidigare forskning inom området. Sökningen genomfördes i databaserna Dentistry of Oral Sciences Source, Medline och Cinahl. Denna litteraturstudie grundas på vetenskapliga invitrostudier med kvantitativ ansats som valdes utifrån inklusions- och exklusionskriterier samt relevanta sökordskombinationer. En urvalsprocess av artiklar utfördes för att säkerställa en systematisk, noggrann samt reliabel presentation av urvalet. Endast artiklar av högkvalitet inkluderades i denna litteraturstudie. Resultat: Resultatet i denna litteraturstudie baserades på en sammanställning av femton vetenskapliga artiklar, som indikerade att xylitol har en inhiberande inverkan på Streptococcus mutans livsduglighet, tillväxt och biofilmbildning, acidogenitet, uppbyggnad, polysackariders kvantitet samt genuttryck. Slutsats: Sammantaget tyder resultatet på att xylitol medför antibakteriell effekt på Streptococcus mutans, genom att hämma dess metaboliska aktiviteter samt virulensfaktorer.

Abstract [en]

Xylitol has been shown to prevent dental caries caused by Streptococcus mutans, a major caries pathogen. Aim: To describe the impact of xylitol on Streptococcus mutans. Method: The study design included a general literature study summarizing the results of previous research in the chosen field. The research was conducted in the databases Dentistry of Oral Sciences Source, Medline and Cinahl. This literature study is based on scientific invitro studies with a quantitative approach that were selected based on inclusion and exclusion criteria and relevant keyword combination. An article selection process was carried out to ensure a systematic, accurate and reliable presentation of the sample. High-quality articles were included in this study. Results: The result of this literature study were based on fifteen scientific articles, which indicated that xylitol has an inhibitory effect on viability, growth and biofilm formation, acidogenicity, structure, polysaccharide amount and gene expression of Streptococcus mutans. Conclusion: The result of this literature study suggest that xylitol has an antibacterial effect on Streptococcus mutans by inhibiting its metabolic activities and virulence factors. 

Place, publisher, year, edition, pages
2024. , p. 24
Keywords [en]
Biofilms, dental caries, sucrose, sweetening agents, virulence factors
Keywords [sv]
Biofilm, karies, sackaros, sötningsmedel, virulensfaktorer
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:hj:diva-65476OAI: oai:DiVA.org:hj-65476DiVA, id: diva2:1879855
Available from: 2024-07-01 Created: 2024-06-28 Last updated: 2025-10-13Bibliographically approved

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