Restless legs syndrome (RLS) is a highly prevalent (i.e.,3% worldwide prevalence) neurologic, sensory-motor circadianrhythm disorder. The discomfort, described by a forced need to move the limbs, ranges from mild and infrequent to severe and limiting. Sig-nificant long-term sleep problems, tiredness, fatigue, and sleepiness during daytime are common, as well as cognitive deficits and depressive symptoms, can in many cases affect the whole life situation. RLS-specific instruments to evaluate the impact on e.g., symptoms and quality of life exist, but have for various reasons been criticized. An alternative to these instruments could be the Ethos Brief Index (EBI) a eight item questionnaire that evaluates Ethos toward wellness. EBI could if valid and reliable be a comprehensive tool in clinical practice and research. The aim of this study was therefore to validate the EBI in patients with RLS.